In the area of recombinant glycoprotein therapeutics for use in humans, the presence of peripherally fucosylated (Lewis-type) glycans is assumed to be a risk when present in cytokines and hormone-like polypeptides. Different forms of N-glycan structures bearing Lewis- or sialyl-Lewis-type structures are available from TheraProteins. In the catalogue only LewisX and sialyl-LewisX structures are contained. For other N-glycans with Lewis or sialyl lewis type (peripheral) fucose please Lewis-type structures play in important role in biological recognition phenomena.contact us: |
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